Direct insertion ins(2;5)
46,XY,ins(2;5)(q14.2;q22q31)
Also known as: insertion, ins(2;5), interchromosomal insertion
46,XY,ins(2;5)(q14.2;q22q31) is a direct interchromosomal insertion: the segment of chromosome 5 between bands 5q22 and 5q31 is removed and inserted into chromosome 2 at band 2q14.2. The carrier is balanced, but the inserted segment can segregate on its own, so a child can inherit a pure duplication or a pure deletion of 5q22-q31.
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What the notation means
46- total chromosome count (the normal human number)
XY- sex chromosomes: one X, one Y (usual male karyotype)
ins(2;5)(q14.2;q22q31)- an INSERTION: the segment between 5q22 and 5q31 of chromosome 5 is moved into chromosome 2 at 2q14.2. Chromosome 2 grows by that piece; chromosome 5 loses it.